University of Washington Genome Sciences Department
Current Instrumentation
Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
Our most sensitive instrument, the Fusion Lumos combines high selectivity and efficiency of transfer for selected ions, along with ultrahigh resolving power and acquisition rates of up to 20 Hz for both Orbitrap and linear ion trap MSn analyses. The tribrid architecture includes a quadrupole mass filter, linear ion trap and an Orbitrap mass analyzer, and the high degree of parallelization of these operations achieves a maximally efficient duty cycle.
TSQ Altis™ Triple Quadrupole Mass Spectrometer
Our triple sector quadrupole Altis can be used in both targeted proteomic and metabolomic applications. It excels in targeted quantitation experiments and retains robustness in complex matrices. This instrument includes segmented quadrupoles to enhance ion transmission and consistency, and ion optics incorporating an ion beam guide with a neutral blocker to provide robust performance and maximum sensitivity.
TSQ Vantage™ Mass Spectrometer
Our TSQ Vantage mass spectrometer excels in targeted proteomics experiments, achieving high throughput detection and quantitation of peptides in complex biological mixtures. The second-generation S-lens optics can handle low flow rates with great desolvation and the second-generation collision cell ensures zero cross-talk during SRM by accelerating the removal of product ions from within the cell before the next precursor is delivered.
Q Exactive™ HF (High Field) Hybrid Quadrupole-Orbitrap™ Mass Spectrometer (I)
The QEHF incorporates an advanced active ion beam guide to increase ion transmission, and its segmented quadrupole mass filter achieves more precise precursor isolation. The eponymous high-field Orbitrap mass analyzer, while physically smaller than its predecessor, provides higher resolution with faster scanning speeds.
Q Exactive™ HF Hybrid Quadrupole-Orbitrap™ Mass Spectrometer (II)
See above.
Velos™ Pro™ Dual-Pressure Linear Ion Trap Mass Spectrometer
The Velos Pro combines speed and robustness with its unique dual-pressure linear ion trap for increased scan-speed, sensitivity, and resolution. The sensitivity and speed are further improved by proprietary S-lens ion optics, combined with Generation II ion optics. In addition, this instrument offers Trap-HCD, CID, PQD, and ETD, thus making it capable of producing ample structural information.
